The role of transposable elements in the function and evolution of centromeres
1 : University of Sussex
Brighton BN1 9RH -
United Kingdom
Transposable elements (TEs) represent the most abundant component of eucaryotic genomes and are key drivers of genomic and phenotypic evolution. Despite their importance, several aspects of their interactions with the host genomes are still not well understood. One of them revolves around their role in the function and evolution of centromeres, regions of ultra conserved function that can, however, rapidly evolve between species. Aided by recent advances in sequencing technologies, we recently showed that TEs are disruptive agents of the genetic and epigenetic environment of centromeres in Arabidopsis thaliana, and are engaged in cycles of invasion and purging through satellite homogenization - processes that drive centromere and genome evolution, and, ultimately, speciation. Taking it further, we now explore the role and dynamics of TEs in centromeres across the tree of life. This talk will cover recently published data, but also new findings from our ongoing work.
| Subject : | : | poster |
| Topics | : | Transposable Elements, Genome Evolution and Adaptation |
| Keywords | : | transposable elements ; centromeres ; genome evolution |
| PDF version | : |  PDF version |
